Calprotectin Turbidimetric High Throughput Testing

Speed, Quality and Flexibility in Calprotectin Quantification

BÜHLMANN fCAL® turbo is a flexible turbidimetric immunoassay for faecal calprotectin applicable on many major clinical chemistry platforms. It is based on the standardization of the BÜHLMANN fCAL® ELISA, which is globally established in laboratories as the gold standard for calprotectin measurements.

The technology of immunoturbidimetry implements a further milestone in faecal calprotectin quantification allowing very rapid and flexible random access use, as well as being the ideal solution for high throughput applications in the routine laboratory.

Run Faecal Tests on the BioSystems BA200

Now you can free up space on your main clinical chemistry analysers by moving faecal calprotectin and elastase assays to the standalone BioSystems BA200 random access analyser. This bench top instrument offers an excellent alternative to the main stream analysers for faecal testing, with comparable performance and efficiency.

Find out more about the BioSystems BA200 standalone analyser

Applications

The BÜHLMANN fCAL® turbo assay can be applied on many automated platforms in clinical chemistry and allows short turnaround time from stool sample to reportable result.

Assay protocols available include:

Siemens:
Advia 1650, Advia 1800, Advia XPT,
Dimension Vista500/1500*
Atellica

Roche:
Cobas 6000 (c501, C502 & c503), Cobas 8000 (c701 & c702),
Cobas c111
Abbott:
Architect c series
Alinity
Mindray:
BS380, BS-200E, BS-400

Beckman:
AU Series (AU400, AU480, AU640, AU680, AU2700, AU5400, AU5800) DxC600 and DxC800
ThermoFisher:
Konelab30i, Indiko
Ortho:
Vitros 5600
The Binding Site:
Optilite
Horiba: ABX Pentra 400
IDS: iSYS
BioSystems BA200

Other instrument protocols currently in validation, please enquire

Complete Automation

The combination of fCAL turbo with the BÜHLMANN CALEX® Cap extraction device strongly simplifies the cumbersome procedure for stool pre-analytics and is ideally adapted for use on clinical chemistry analysers.

No additional pipetting and manual dilution steps are required anymore.

Recent modifications to the CALEX design enable it to be used on laboratory track systems to provide complete automation for faecal calprotectin testing with minimal hands on time.

Benefits

Method	Particle-enhanced turbidimetric immunoassay (PETIA)
Method	Particle-enhanced turbidimetric immunoassay (PETIA)	Sample Type	Faecal extracts
Method	Particle-enhanced turbidimetric immunoassay (PETIA)	Kit Format	2 reagents; wedge bottles for direct loading on many platforms Reagents last for ~200 tests; platform dependent All assay components are also available individually
Method	Particle-enhanced turbidimetric immunoassay (PETIA)	Sample Preparation	CALEX® Cap extracts can be used directly without additional dilution
Method	Particle-enhanced turbidimetric immunoassay (PETIA)	Reagent on Board	Stable for at least 60 days
Method	Particle-enhanced turbidimetric immunoassay (PETIA)	Calibration	Stable for up to 60 days
Method	Particle-enhanced turbidimetric immunoassay (PETIA)	Calibration Range	0-2000 μg/g
Method	Particle-enhanced turbidimetric immunoassay (PETIA)	Measuring Range	20-8000 μg/g
Method	Particle-enhanced turbidimetric immunoassay (PETIA)	Sample Volume	~10 µl Extract (1:500)
Method	Particle-enhanced turbidimetric immunoassay (PETIA)	Time to Result	~10 minutes
Method	Particle-enhanced turbidimetric immunoassay (PETIA)	Applicable	On many major platforms